Longer-term clinical depression, also called major depressive disorder (MDD), causes symptoms most of the day, nearly every day. In addition to low energy, fatigue, and lack of motivation, you have symptoms such as:
- Feeling hopeless, worthless, and sad
- Feeling anxious and irritable
- Avoiding family and friends
- Loss of interest in your favorite activities
- Eating either too much or too little
- Gaining or losing weight
- Sleeping too much or not being able to sleep
- Being unable to concentrate or make decisions
- Thinking about suicide or harming yourself
You may also have physical symptoms. MDD commonly causes muscle aches, joint pain, and chronic pain.